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艾美捷LKT Labs AB-680#A040068参数说明:
Cas No.:2105904-82-1
纯度:≥98%
公式:C20H24氯氟乙烯4O9P2
配方重量:580.83
IUPAC名称:[[(2R,3S,4R,5R)-5-[6-氯-4-[[(1S)-1-(2-氟苯基)乙基]氨基]吡唑并[3,4-b]吡啶-1-基]-3,4-二羟基氧代-2-基]甲氧基羟基磷酸基]甲基膦酸
同义词:AB680, 奎姆利卢司他
外观:类白色粉末
储存温度:-20°C
LKT Labs-AB-680文献引用:
Faraoni E, Strickland L, O’Brien B, et al. Radiofrequency ablation in combination with CD73 inhibitor AB680 reduces tumor growth and enhances anti-tumor immunity in a syngeneic model of pancreatic ductal adenocarcinoma. Front Oncol. 2022 Sep 6;12:995027. PMID: 36147911
Noh J, Lee I, Han N, et al. Additive effect of CD73 inhibitor in colorectal cancer treatment with CDK4/6 inhibitor through regulation of PD-L1. Cell Mol Gastroenterol Hepatol. 2022;14(4):769-788. PMID: 35843546
Kim M, Min Y, Jang J, et al. Single-cell RNA sequencing reveals distinct cellular factors for response to immunotherapy targeting CD73 and PD-1 in colorectal cancer. J Immunother Cancer. 2021 Jul;9(7):e002503. PMID: 34253638
LKT Laboratories(LKT Labs)注于防癌抗癌特殊化学品研究和开发域。主要包括:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成等。同时注研究用小分子的合成,纯化和分离。主要应用于癌症和神经科学等,包括蛋白激酶抑制剂、离子通道调节剂和激活剂等。艾美捷科技是LKT Labs的中国代理商,为科研工作者提供优质的产品与服务。
来源:https://www.amyjet.com/news/LKT-Laboratories-new.shtml