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技术文章

GAB1 Antibody (Y259) Catalog Number:OM233625

点击次数:42 发布时间:2024/9/14 13:58:19
 

Product Profile

Product Name GAB1 Antibody (Y259)
Antibody Type Primary Antibodies

Key Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

IHC

 
IHC~~1:10~50:
Species Reactivity

Human

Concentration 1 mg/ml
Purification  

Target Information

Alternative Names
GAB1
GRB2-associated-binding protein 1
GRB2-associated binder 1
Growth factor receptor bound protein 2-associated protein 1
More 
Molecular Weight(MW) 76616 Da
Function
Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR)
Tissue Specificity This GAB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding Y259 of human GAB1.

Database Links

Entrez Gene 2549

Application

  • Application

    Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with GAB1 Antibody (Y259) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Application Notes
IHC~~1:10~50:

Additional Information

Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

原创作者:上海笃玛生物科技有限公司

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