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技术文章

DLK1 antibody Catalog Number:OM250156

点击次数:33 发布时间:2024/9/23 15:04:18
  

Product Profile

Product Name DLK1 antibody
Antibody Type Primary Antibodies
Product description
Mouse Monoclonal Antibody [3A10] to DLK1This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass. [provided by RefSeq, Mar 2010]
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Immunogen
The immunogen corresponding to human DLK1 expressed in E. Coli.

Key Feature

Clonality Monoclonal
Isotype IgG1
Clone Number 3A10
Host Species Mouse
Tested Applications

ELISAFACSICC/IFWB

 
ELISA: 1/10000.:
Species Reactivity

Human

Concentration 1 mg/ml
Purification  

Target Information

Gene Synonyms
DLK-1
DELTA1
ZOG
PREF1
PG2
FA1
DLK
PREF-1
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Target DLK1
Molecular Weight(MW) 41 kDa (note)

Application

  • Application

    ELISA analysis of control antigen and antigen using DLK1 antibody [3A10].

  • Application

    WB analysis of human DLK1 (a.a. 174-349) recombinant protein using DLK1 antibody [3A10].

  • Application

    ICC/IF analysis of U251 cells using DLK1 antibody [3A10] (green), Alexa Fluor-555 phalloidin (red) and DRAQ5 fluorescent DNA dye (blue).

  • Application

    FACS analysis of NIH3T3 cells using DLK1 antibody [3A10] (green) or a negative control (red).

Application Notes
ELISA: 1/10000.:

Additional Information

Form Liquid
Storage Instructions 4°C; -20°C for long term storage
Storage Buffer Ascitic fluid containing 0.03% sodium azide.
 

原创作者:上海笃玛生物科技有限公司

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