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技术文章

MCM2 Antibody Catalog Number:OM284351

点击次数:34 发布时间:2024/9/27 14:30:09
 

Product Profile

Product Name MCM2 Antibody
Antibody Type Primary Antibodies
Product description
MCM2, also called DNA replication licensing factor MCM2, Minichromosome maintenance protein 2 homolog or Nuclear Protein BM28) is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by protein kinases CDC2 and CDC7. Double serines at positions 26 and 27 are conserved in rat and mouse. High homology >88% to similar proteins from several other species. Expected broad reactivity to various lysates.
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Immunogen
MCM2 antibody was raised against amino acids 21 - 31 of MCM2 (Human).

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

ELISAIFIHCWB

 
MCM2 antibody can be used in Western Blot, and immunohistochemistry starting at 10 μg/mL.:
Species Reactivity

HumanMouseRatYeast

Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol MCM2
Alternative Names
MCM2
BM28
Cell devision cycle-like 1
D3S3194
Cdc19
Cyclin-like 1
KIAA0030
Nuclear protein BM28
CDCL1
MITOTIN
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Database Links

Entrez Gene 4171
Protein Accession P49736

Application

  • Application

    Immunohistochemistry staining of MCM2 in skin tissue using MCM2 Antibody.

Application Notes
MCM2 antibody can be used in Western Blot, and immunohistochemistry starting at 10 μg/mL.:

Additional Information

Form Liquid
Storage Instructions Aliquot and store MCM2 antibody at -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Storage Buffer 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.

原创作者:上海笃玛生物科技有限公司

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