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技术文章

MCM2 antibody Catalog Number:OM262647

点击次数:39 发布时间:2024/9/27 14:45:06
 

Product Profile

Product Name MCM2 antibody
Antibody Type Primary Antibodies
Product description
Mouse monoclonal antibody [CRCT2.1] to MCM2The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]
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Immunogen
Bacterially expressed human Mcm2.

Key Feature

Clonality Monoclonal
Isotype IgG1
Clone Number CRCT2.1
Host Species Mouse
Tested Applications

IHC-FIHC-PWB

 
Immunohistology - Frozen: 1/500 - 1/1000:
Species Reactivity

Human

Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Synonyms
minichromosome maintenance complex component 2
CCNL1
MITOTIN
CDCL1
D3S3194
BM28
cdc19
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Target MCM2
Tissue Specificity This antibody recognizes human DNA replication licensing factor MCM2.

Application

  • Application

    IHC-P analysis of human tonsil tissue using MCM2 antibody [CRCT2.1 (D1.9H5)].

Application Notes
Immunohistology - Frozen: 1/500 - 1/1000:

Additional Information

Form Liquid
Storage Instructions Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage Buffer Phosphate buffered saline containing 0.09% Sodium Azide

原创作者:上海笃玛生物科技有限公司

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