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技术文章

Pinch-1/2 Antibody (H-300) Catalog Number:OM188742

点击次数:31 发布时间:2024/9/29 14:13:15
 

Product Profile

Product Name Pinch-1/2 Antibody (H-300)
Antibody Type Primary Antibodies
Modification Notes Pinch is a focal adhesion protein that is a component of the ILK-PINCH complex. This complex is a major part of the growth factor and integrin signaling pathway. Pinch is involved in cell differentiation, proliferation and survival by acting as an effector of integrin and growth factor signaling. It is a cylasmic protein expressed in most tissues and consists of five LIM domains, a nuclear localization signal and a nuclear export signal. The PINCH-1/ILK complex is regulated by another member of the Pinch family, PINCH-2, which also forms a complex with ILK.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WBIPIFELISA

 
recommended for detection of Pinch-1 and Pinch-2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian:
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

Target Information

Alternative Names
epie corresponding to amino acids 1-300 mapping at the N-terminus of Pinch-1 of human origin
Tissue Specificity epie corresponding to amino acids 1-300 mapping at the N-terminus of Pinch-1 of human origin

Database Links

Entrez Gene 3987

Application

  • Application

    Western blot analysis of Pinch-1/2 expression in T98G (A) and COLO 320DM (B) whole cell lysates.

  • Application

    Western blot analysis of Pinch-1/2 expression in human platelets whole cell lysate.

Application Notes
recommended for detection of Pinch-1 and Pinch-2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian:

Additional Information

Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

原创作者:上海笃玛生物科技有限公司

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