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技术文章
Anti-RAB21 antibody Catalog Number：OM642604
点击次数：43 发布时间：2024/10/8 15:24:41
Product Profile
| Product Name | Anti-RAB21 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFIHC |
| IHC:1:200-1:2000 ICC/IF:1:100-1:500 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
Target Information
| Gene Symbol | RAB21 |
|---|---|
| Gene Synonyms | |
| Gene Full Name | RAB21, member RAS oncogene family |
| Gene Summary | This gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion ａnd migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by the tumor suppressor miR-200b, ａnd miRNA-200b is itself downregulated in glioma tissues. [provided by RefSeq, Nov 2015] More |
| Molecular Weight(MW) | 24KD |
| Cellular Localization | Cell projection, Cylasmic vesicle, Endoplasmic reticulum, Endosome, Golgi apparatus, Membrane |
Application
-
IHC
Immunohistochemical analysis of paraffin-em
bedded lung cancer tissues using RAB21 antibody with DAB staining. -
IHC
Immunohistochemical analysis of paraffin-em
bedded renal carcinoma tissues using RAB21 antibody with DAB staining. -
ICC/IF
Immunofluorescence analysis of A549 cells using RAB21 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
| Application Notes | IHC:1:200-1:2000 ICC/IF:1:100-1:500 |
|---|
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
原创作者：上海笃玛生物科技有限公司
