产品展示
Recombinant Murine IL-3 Peprotech北京厂家
点击次数：30发布时间：2016/1/26 13:43:52
更新日期：2016/1/26 13:43:52
所 在 地：中国大陆
产品型号：213-13
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详细内容
产品编号:
213-13
别名:
MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor
描述:
IL-3 is a hematopoietic growth factor that promotes the survival, differentiation ａnd proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil ａnd mast cell lineages. Produced by T cells, mast cells ａnd eosinophils, IL-3 enhances thrombopoiesis, phagocytosis, ａnd antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is a species-specific, variably glycosylated cytokine. Recombinant Murine IL-3 is a 15.1 kDa globular protein containing 135 amino acid residues.
氨基酸序列:
MDTHRLTRTL NCSSIVKEII GKLPEPELKT DDEGPSLRNK SFRRVNLSKF VESQGEVDPE DRYVIKSNLQ KLNCCLPTSA NDSALPGVFI RDLDDFRKKL RFYMVHLNDL ETVLTSRPPQ PASGSVSPNR GTVEC
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
生物活性:
The ED50 as determined by the dose-dependent stimulation of the proliferation of murine NFS-60 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.
交叉反应:
Gerbil, Rat, Mouse, Human, Bacteria, Monkey, Mouse + Virus
研究领域:
原产国:
USA
仅用于研究。不适用于诊断或治疗。
