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Recombinant Murine IL-6 Peprotech新品促销
点击次数：36发布时间：2016/1/26 14:02:21
更新日期：2016/1/26 14:02:21
所 在 地：中国大陆
产品型号：216-16
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详细内容
产品编号:
216-16
别名:
26 kDa protein, IFN-b2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2
描述:
IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune ａnd inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells ａnd keratinocytes, IL-6 has diverse biological functions. It stimulates B cell differentiation ａnd antibody production, synergizes with IL-3 in megakaryocyte development ａnd platelet production, induces expression of hepatic acute-phase proteins, ａnd regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R α ａnd gp130. Murine IL-6 is inactive on human cells, while both human ａnd murine are equally active on murine cells. Recombinant Murine IL-6 is a 21.7 kDa protein containing 188 amino acid residues.
氨基酸序列:
MFPTSQVRRG DFTEDTTPNR PVYTTSQVGG LITHVLWEIV EMRKELCNGN SDCMNNDDAL AENNLKLPEI QRNDGCYQTG YNQEICLLKI SSGLLEYHSY LEYMKNNLKD NKKDKARVLQ RDTETLIHIF NQEVKDLHKI VLPTPISNAL LTDKLESQKE WLRTKTIQFI LKSLEEFLKV TLRSTRQT
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
生物活性:
The ED50 as determined by the dose-dependent stimulation of the proliferation of IL-6-dependent murine 7TD1 cells is ≤ 0.02 ng/ml, corresponding to a specific activity of ≥ 5 x 107 units/mg.
交叉反应:
Monkey, Mouse, Trout, Rat, Mouse + Bacteria, Human + Mouse, Mouse + Virus
研究领域:
原产国:
USA
仅用于研究。不适用于诊断或治疗。
