产品展示
Recombinant Murine IL-10 Peprotech 优势产品
点击次数：44发布时间：2016/1/26 14:07:46
更新日期：2016/1/26 14:07:46
所 在 地：中国大陆
产品型号：210-10
优质供应
详细内容
产品编号:
210-10
别名:
B-TCGF, CSIF, TGIF
描述:
IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells ａnd keratinocytes. IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 ａnd TNF-α. Like IL-4, IL-10 enhances humoral immune responses ａnd attenuates cell-mediated immune reactions. Human IL-10 is active on murine cells, but murine IL-10 is inactive on human cells. Recombinant Murine IL-10 is an 18.7 kDa protein of 161 amino acid residues.
氨基酸序列:
MSRGQYSRED NNCTHFPVGQ SHMLLELRTA FSQVKTFFQT KDQLDNILLT DSLMQDFKGY LGCQALSEMI QFYLVEVMPQ AEKHGPEIKE HLNSLGQKLK TLRMRLRRCH RFLPCENKSK AVEQVKSDFN KLEDQGVYKA MNEFDIFINC IEAYMMIKMK S
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
生物活性:
PeproTech＇s Murine IL-10 is fully biologically active as measured by the dose-dependent co-stimulation (with IL-4) of the proliferation of murine MC/9 cells. The ED50 was found to be < 2 ng/ml, corresponding to a specific activity of > 5 x 105 units/mg.
交叉反应:
Human, Mouse, Rat
研究领域:
原产国:
USA
仅用于研究。不适用于诊断或治疗。
